Keynote series Dr. Adeel Razi — How does psilocybin rewire our brains?

This study examines the effects of psilocybin on brain connectivity using fMRI and EEG, revealing increased activity in regions tied to cognition, emotion, and imagination while reducing sensory processing, leading to a blended state of "embeddedness." Machine learning analysis linked structured brain activity to stronger psychological effects, with long-term changes in perception and acceptance of mortality observed a month later. Context was crucial, music enhanced emotional depth, while meditation had no significant impact. On a neural level, psilocybin altered brainwave patterns, promoting more flexible and creative processing, emphasizing the importance of environmental factors in shaping psychedelic experiences.